Basic Principles of the QuEChERs Method

The basic principle of the QuEChERs method is similar to that of high performance liquid chromatography (HPLC) and solid phase extraction (SPE). It uses the adsorbent filler to interact with impurities in the matrix to adsorb impurities and achieve the purpose of impurity removal. Specifically, after the homogenized sample is extracted by acetonitrile (or acidified acetonitrile), the salt is separated and layered by extraction salt, and the matrix dispersive extraction mechanism is used, and PSA or other adsorbent and most of the interfering substances in the matrix are used (organic Acid, fatty acid, carbohydrate, etc. are combined and removed by centrifugation to achieve purification.

There are many applications in the QuEchERS method. As long as the recovery rate of the target to be tested meets the demand, and the matrix background of the impurity removal meets the detection requirements, the method can be used to purify the food residue, animal residue, additives, and illegal. Additives, plasticizers, all areas may be involved. However, the current QuEchERS method is mainly used in the detection of pesticide residues in agricultural products.